Summary: Necroptotic cell death has been implicated in many human pathologies and is thought to have evolved as an innate immunity mechanism.The pathway relies on two key effectors: the kinase receptor-interacting protein kinase 3 (RIPK3) and the terminal effector, the pseudokinase mixed-lineage kinase-domain-like (MLKL).We identify proteins with h
The purpose of this study was two-fold.The first was to investigate the pathologic mechanisms underlying the formation of subdural fluid collection, an umbrella term referring to a condition commonly seen in the clinical setting.Accumulation of the cerebrospinal fluid (CSF) in the subdural space can be referred to in this disease category, disregar
Home healthcare has become more and more central in the last decades, due to the advantages it can bring to both healthcare institutions and patients.Planning activities in this context, however, presents significant challenges related to route planning and mutual synchronization of caregivers.In this paper we propose a new compact Leather Flask mo